frealign v8
an alignment program for single-particle reconstruction (includes examples) (11 Mb). The development of the program FREALIGN was begun in 1997 at the MRC Laboratory of Molecular Biology in Cambridge, UK with financial support from the MRC and the Deutsche Forschungsgesellschaft. Contributions to the program code were made by:
Nikolaus Grigorieff
Richard Henderson
Christine Villaneuve
Matthias Wolf
Papers describing or utilizing FREALIGN are:
FREALIGN: High-resolution refinement of single particle structures.
J Struct Biol. 2006 Jun 2, Grigorieff NEwald sphere correction for single-particle electron microscopy.
Ultramicroscopy. 2006 Mar;106(4-5):376-82, Wolf M, DeRosier DJ, Grigorieff NNoise bias in the refinement of structures derived from single particles.
Ultramicroscopy. 2004 Dec;102(1):67-84, Stewart A and Grigorieff NThree-dimensional structure of bovine NADH:ubiquinone oxidoreductase (complex I) at 22 A in ice.
J Mol Biol. 1998 Apr 17;277(5):1033-46, Grigorieff NThis software is licensed under the terms of the GNU Public License version 3 (GPLv3).
If you have trouble compiling or using these programs, please contact Niko Grigorieff for instructions.